|
KMID : 0361020120550060364
|
|
Korean Journal of Otolaryngology - Head and Neck Surgery
2012 Volume.55 No. 6 p.364 ~ p.368
|
|
|
Value of 18F-Fluorodeoxyglucose Position Emission Tomography/Computed Tomography in Diagnosis of Cervical Lymph Node Metastasis of Head and Neck Squamous Cell Carcinoma: Comparison with Computed Tomography and Magnetic Resonance Imaging
|
|
Kim Jong-Min
Ji Yong-Bae
Choi Yoon-Young
Kim Ji-Young
Park Jeong-Seon
Lee Young-Jun
Tae Kyung
|
|
|
Abstract
|
|
|
Background and Objectives: Cervical lymph node metastasis is a very important prognostic factor of head and neck squamous cell carcinoma (HNSCC). Therefore, strict evaluation of cervical lymph node metastasis is necessary for accurate staging and proper treatment planning. This study compares computed tomography (CT) and magnetic resonance imaging (MRI) to position emission tomography-computed tomography (PET-CT), and evaluates the clinical role of PET-CT in the diagnosis of cervical metastasis of HNSCC.
Subjects and Method: From October 2004 to September 2010, we studied 74 patients with HNSCC who underwent PET-CT, CT and MRI before undergoing neck dissection for the treatment of cervical lymph node metastasis. We compared pathologic results of 374 cervical lymph node levels in 74 patients with results of PET-CT, CT and MRI. We analyzed and compared sensitivity, specificity, predictability and accuracy of the three imaging methods.
Results: Among the 74 patients, 49 (66.2%) patients had positive cervical lymph node metastasis. Of the 374 cervical lymph node levels, 86 levels were confirmed to be positive lymph node metastasis. Sensitivity and specificity of PET-CT was 87.4% and 94.8% when the cut-off value of SUVmax was 1.855. Sensitivity, specificity, positive and negative predictive value and accuracy of PET-CT were higher than those of CT or MRI.
Conclusion: PET-CT is more effective than CT or MRI in the diagnosis of cervical lymph node metastasis of HNSCC.
|
|
|
KEYWORD
|
|
|
Head and neck cancer, PET, CT, MRI, Lymph node
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|